You make the
family. We help.
Ready to have a
Prelude has partnered with one of the nation’s leading fertility clinics and the nation’s largest frozen donor egg bank—My Egg Bank North America—to offer you the latest reproductive science and technology services. You’ll understand your choices and feel confident that whatever option you choose, you'll have dramatically higher chances of success.
Donor eggs work!
What are your requirements for donors, and how are they screened?
Prelude’s donors include women of all ethnicities between the ages of 21 to 30 who are screened to ensure good general and reproductive health, a clear genetic history, and psychological stability. Donors must meet specific height/weight requirements to assure medications used during the stimulation cycle will work effectively. They must also meet all screening guidelines required by the FDA and ASRM, as well as pass a rigorous genetic workup that includes: consultation with a certified genetic counselor, personal and family health history, and genetic testing for inherited genetic diseases.
What is the difference between fresh and frozen donor cycles?
Fresh egg donation cycles involve stimulation of the donor, retrieval, and insemination of her eggs, with transfer to the recipient, all within a few weeks. With a frozen donor egg cycle, donors are treated in advance, and the eggs are collected and frozen for future use. Recipients using frozen eggs will select their donor. There is no significant difference in IVF success rates between embryos produced by fresh or frozen eggs.
Is there an age cutoff to be a recipient?
We accept women up to age 55 for our recipient program. Women between the ages of 45 and 50 must have a medical clearance and a perinatal specialist’s clearance prior to entering the program. Women between the ages of 51 and 55 must have a medical clearance and a perinatal specialist’s clearance, as well as no serious chronic health illnesses. The embryo transfer must be completed prior to the woman's 56th birthday.
Will the donor know if a pregnancy occurred?
We do not inform donors of the success or failure of the donation. However, we do invite some donors to make additional donations. These donors may conclude they are being invited back because they initiated a pregnancy.
What are the advantages of using Prelude's frozen donated eggs?
Prelude relies on rapid egg freezing technology, or vitrification, which is:
- More economical—more efficient than traditional egg donation and typically less expensive.
- More convenient—treatment can begin immediately and there is no delay in waiting for a donor match or for donor/recipient menstrual synchronization.
- Recipient-friendly—the donor selection process gives recipients more choice and control.
In addition to freezing patients’ own eggs, Prelude aims to provide infertile women with access to the largest inventory of frozen donor eggs in the United States, eliminating the six- to nine-month matching -wait associated with many egg donation programs.
Prelude also gives people complete control over the donor egg selection process, as recipients have full access to all information (physical and intellectual attributes, as well as family medical history) for every donor in the frozen egg database.
What are the requirements to become a recipient?
We accept women up to age 55 for our recipient program. Women between the ages of 45 and 55 must have a medical clearance and a perinatal specialist’s clearance prior to entering the program. While network affiliates’ requirements may vary slightly, generally speaking, a physician consult, screening bloodwork and cultures, pap smear, mammogram (>40 yrs), flexible sigmoidoscopy (>50 yrs), medical clearance letter (>45 yrs), uterine evaluation, sounding (trial embryo transfer), and a psychological consult are typically required. The male partner will also need screening bloodwork and a semen analysis.
What is the time frame for a cycle?
Frozen donor cycles through a Prelude network provider take about four weeks to complete.
Can my OB/GYN do some of my initial testing to take advantage of my insurance coverage?
Yes, most affiliate centers can write an order to have your OB/GYN perform some of the screening.
What is the percentage of success with each treatment cycle?
Success rates for egg bank recipients through December 2012 are as follows:
- The overall pregnancy rate is approximately 60 percent.
- The elective single embryo transfer pregnancy rate is also about 60 percent.
- The double embryo transfer rate is approximately 70 percent. (Pregnancies from double embryo transfer have a 50 percent chance of being twins, and for this reason Prelude strongly advises single embryo transfer whenever possible.)
None of this data is recorded with Center for Disease Control (CDC) or Society for Assisted Reproductive Technology (SART). To date, the CDC and SART registries do not include donor egg treatment cycles from frozen eggs. RBA has consistently shown pregnancy rates in excess of 60 percent for the last 10 years (except in 2005) in egg donation cycles initiated with fresh donor eggs, and in the transition from primarily “fresh” egg donation to “frozen egg” donation, RBA and now Prelude have not seen any decline in overall pregnancy and delivery rates.
Can I see a photo of the donor?
No adult photos of the donor will be shared, but three to four childhood photos up to age 7 will appear on the website if given permission to view them. Anyone with Internet access can view the list of available donors and see their age, hair color, eye color, height, weight, and education level. Recipients who are registered and have been approved by Prelude will also have access to the donor’s childhood photograph(s) and profile on the website, but the photographs and profile will have no identifying information associated with them.
What information is given to me about the donor?
You will receive a copy of the donor's profile, family medical history, and genetics report.
How can I assess the personality of my donor?
Every donor who is approved and listed on the web site has gone through a full battery of psychological tests. We are not in a position to make a full assessment of the donor's personality beyond what we can read in the psychological report. Be assured, however, that all of the donors are screened very carefully and that donors at risk for any kind of psychological problem are excluded prior to treatment.
How do you find your donors? Do you recruit or advertise?
We advertise for egg donors locally and at colleges and universities through various online media, radio, some print publications, and occasionally billboards. A large number of donors are referred by friends who have previously donated to Prelude.
Are all your donors college-educated?
No, but we have a strong preference for college-educated donors. Our donors who have not graduated from college generally have some other highly desirable trait(s) to make them candidates for our program. We review each egg donor's personal background thoroughly before accepting her into our program.
How does the matching process work?
With fresh-egg donation cycles, the donor coordinators and physicians try to find and offer the closest possible match to what the recipient desires in her donor.
The Prelude website contains a database of information about all our available egg donors. Recipients have the opportunity to review the available donors and forward their selection choices to the donor coordinators.
Can I exercise while going through treatment?
Exercise is not contraindicated during your recipient cycle; however, once the embryo transfer is performed, you will want to only perform low-impact exercise until your pregnancy test.
What are the side effects of the medications I will be taking?
Some of the possible side effects of the cycle medications include headaches, hot flashes, minimal weight gain, water retention, and mood swings.
Can I travel during treatment?
Once your recipient cycle begins, it is important to be available for any needed appointments. Your nurse, prior to your cycle, can assist you in planning for these appointments.
Who do I call with questions?
During the matching and treatment process, we encourage you to contact the donor coordinator of your home center with any questions. Some questions may be directed by your home center to the Prelude staff.
When can we have intercourse after the embryo transfer and if I am pregnant?
After your transfer, we ask that you refrain from intercourse until your pregnancy test, approximately 10-12 days later. If you are pregnant, as long as you are not experiencing bleeding or discomfort, intercourse is not contraindicated.
Can I fly on a plane after my embryo transfer?
Air travel should be fine following the embryo transfer.
If I am pregnant, is it normal to lightly spot or have some abdominal cramping?
Spotting (dark red or brown) can be quite normal early in pregnancy. However, if you experience bright red bleeding that soaks a pad in an hour, immediately get off your feet and call our office.
Intermittent mild cramping and slight twinges on either side may also be normal. If cramping is moderate to severe, and not relieved by Tylenol, this may not be normal and you should notify our office.
When will I be able to tell if I am pregnant?
Pregnancy testing is scheduled 10-12 days after the embryo transfer, depending on the stage of the embryos at transfer.
How long will I stay with the practice once I am pregnant?
Typically you will not be discharged to your OB/GYN until 8–10 weeks of pregnancy. You will have several blood tests and ultrasounds to determine appropriate growth of the pregnancy before you are released.
Do I need to divulge to anyone that I used donated eggs?
Pursuing donor eggs as a treatment option is a very personal decision. It is patient preference to share this information with others. We do recommend sharing this information with your OB/GYN, as he/she will be continuing your care once you are discharged from our practice.
Current data from psychological journals on this subject suggest disclosing this information to the child at the appropriate time in the future.
Can I be a recipient if I have had my fallopian tubes removed or am menopausal?
Is it necessary when being matched with a donor to have a blood type match?
No, unless you are planning on not disclosing the egg donation to your child.
Can I go to my pharmacy to purchase my cycle medications?
Yes, you may use your regular pharmacy to purchase your medications for your recipient cycle. However, some of the medications may need to be preordered, as some pharmacies may not keep some of the medications in stock.