Pacific Fertility Center: San Francisco

55 Francisco Street, Suite 500 San Francisco, CA 94133 415-834-3095 pacificfertilitycenter.com

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· First clinic to conduct ICSI in Northern California
· Leading provider of egg freezing services in the Bay Area
· For our Mandarin-speaking patients, a full care team fluent in your native language
· Helped families of every kind create over 10,000 babies

Meet the Team

Philip E. Chenette, M.D.

Philip E. Chenette, M.D.Reproductive Endocrinologist

Dr. Chenette is one of the “Best Doctors in America” as rated by his peers and is a recognized "Top Doctor" in consumer guides to top medical care. Dr. Chenette is a past recipient of the American Fertility Association’s (AFA) Family Building Award. He is an Assistant Clinical Professor with the Volunteer Clinical Faculty (VCF) in Obstetrics, Gynecology, and Reproductive Sciences at the University of California San Francisco (UCSF). Dr. Chenette’s compassion and experienced approach to treating complex infertility conditions places him among the very best fertility doctors and fertility specialists in the nation. A native of Chicago, Dr. Chenette is an internationally recognized Board Certified specialist in Reproductive Endocrinology and Infertility. He obtained his MD degree from Indiana University Medical School in 1983, graduated with Honors in Academic Medicine, and was selected to participate in the Clinical Scholars Program at the National Institutes of Health (NIH). After completing residency training at Magee-Women’s Hospital of the University of Pittsburgh in 1987, Dr. Chenette completed fellowship in Reproductive Endocrinology and Infertility at the University of Southern California (USC) in 1989. After fellowship, he was appointed to the teaching faculty at Northwestern University in Chicago. While on the faculty, Dr. Chenette started the prestigious and successful IVF program at Northwestern. Dr. Chenette joined Pacific Fertility Center and moved to San Francisco in 1991. In 1992 he joined the San Francisco Center for Reproductive Medicine where he served as Director of IVF. In November of 1999, Dr. Chenette along with his partners merged practices to form Pacific Fertility Center.

As a researcher, Dr. Chenette has authored a number of articles that have been published in various national and international medical journals. He is engaged in advanced research projects in computer embryo imaging to improve pregnancy rates, Comprehensive Chromosome Screening (CCS) as a way to enable single embryo transfer, and in egg freezing. Dr. Chenette speaks several computer ‘languages’ including SQL and Objective-C. Dr. Chenette’s fertility research into unique embryo transfer techniques resulted in US patent #5,360,389 "Methods for endometrial implantation of embryos". Dr. Chenette has spent the last twenty years specializing in the treatment of patients with complex infertility diagnoses and women over 40. In clinical care he emphasizes Comprehensive Chromosome Screening (CCS) to minimize the risk of chromosomal disorders like Downs’ Syndrome and to maximize success rates while minimizing risk. He brings advanced management techniques like SixSigma to fertility clinic management. He is director of Pacific Fertility Center’s Egg Freezing Program. Throughout his career, Dr. Chenette has dedicated himself to the pursuit of excellence in medicine. Dr. Chenette is also the president for the 2018 PCRS meeting. In his free time, Dr. Chenette enjoys spending time with his family and playing the piano, oboe, and guitar, piloting a plane, skiing and bicycling.

Carolyn R. Givens, M.D.

Carolyn R. Givens, M.D.Reproductive Endocrinologist

Dr. Carolyn Givens is Board-Certified by The American Board of Obstetrics and Gynecology in both Obstetrics and Gynecology and in Reproductive Endocrinology and Infertility and has spent the majority of her career helping couples with infertility. She attended the University of Texas, graduating magna cum laude with a B.S. degree in Molecular Biology. She received her medical degree from the University of Texas Southwestern Medical School in 1986 and served a residency in Obstetrics and Gynecology at Parkland Memorial Hospital from 1986 to 1990. Dr. Givens moved to San Francisco in 1990 to continue her training in Reproductive Endocrinology and Infertility at the University of California, San Francisco. After fellowship training, she was invited to join the medical school faculty at UCSF. During her seven years on faculty at the University of California, San Francisco, she developed particular interest in severe male factor infertility and genetic problems associated with infertility. Dr. Givens was concurrently a full-time clinician with the UCSF In Vitro Fertilization Program and an Assistant Professor of the UCSF Medical School. As a faculty member, she focused on infertility patient therapy, infertility clinical research and training other infertility specialists. Although her career has focused on assisted reproduction, infertility and egg donation treatment, she is a skilled practitioner of all aspects of infertility care including physician-assisted ovulation induction and insemination, and surgical procedures such as laparoscopy and hysteroscopy. Dr. Givens is an accomplished clinical researcher and author of numerous articles for peer-reviewed professional journals.

In November of 1999, Dr. Givens left UCSF and joined the infertility specialists at Pacific Fertility Center. She currently co-directs the Bay Area Pre-Implantation Genetic Diagnosis Program (PGD) and directs Pacific Fertility Center’s PGD/PGS Program. She has been named since 2004 as one of "Best Doctors in America" and by her peers in a national survey. Dr. Givens served as President of the Pacific Coast Reproductive Society for 2010-2011 and has served on the Board of the Society from 2000-present. She remains actively involved locally in the San Francisco Ob/Gyn Society and as a member of the Obstetrics and Gynecology Department at California Pacific Medical Center (a leading Bay Area hospital group) and serves as a reviewer for the journals Fertility and Sterility, Endocrinology and Obstetrics and Gynecology. She is a member of the American Society for Reproductive Medicine, Pacific Coast Reproductive Society and the Society for Reproductive Endocrinology and Infertility, among many other organizations and societies.

Carl M. Herbert, M.D.

Carl M. Herbert, M.D.Reproductive Endocrinologist

Dr. Herbert is a fourth-generation physician who graduated from the University of Florida as a member of the Alpha Omega Alpha Medical Honor Society. He completed both a residency in Obstetrics and Gynecology and a fellowship in Reproductive Endocrinology at Vanderbilt University Medical Center. Dr. Herbert joined the Vanderbilt teaching faculty upon completion of his fellowship and served as the Director of the Reproductive Endocrinology Division from 1989-90. He is an accomplished clinical researcher and author of numerous articles and chapters for professional medical publications. In 1982 Dr. Herbert was instrumental in the development of one of the first assisted reproductive technology programs in the United States at Vanderbilt University Medical Center. He is an internationally recognized fertility specialist who has been performing in-vitro fertilization longer than any other physician in the Bay Area. This experience provides him with a unique perspective as he incorporates the latest developments in reproductive technology into patient care. Dr. Herbert is Board Certified by The American Board of Obstetrics and Gynecology in both Obstetrics and Gynecology and in Reproductive Endocrinology and Infertility. In 1990 Dr. Herbert came to San Francisco clinic and began delivering private practice ART care. He served as the Medical Director for two different clinics including the San Francisco Center for Reproductive Medicine. Under Dr. Herbert's stewardship, SFCRM became a leading center for infertility care and assisted reproductive technology services. His leadership in the community was recognized in 1996 when he was appointed Director of the Division of Reproductive Endocrinology and Infertility at California Pacific Medical Center.

Desiring to combine the personal care and attention of a private practice with more involvement in reproductive research and leading edge advances, Dr. Herbert collaborated with a long-time friend and colleague, Dr. Eldon Schriock. They, together with their partners, purchased and reorganized Pacific Fertility Center in November of 1999. Dr. Herbert is the president of Pacific Fertility Center and he continues to be involved with reproductive research maintaining an active interest in the ethical dilemmas confronting reproductive technologists in the 21st century. Dr. Herbert served as 2002-3 President of the Society For Humanism in Medicine and spearheaded their CME program "The Human Embryo: Issues Surrounding the Beginnings of Life." Dr. Herbert has repeatedly been singled out by his peers in two independent national surveys "Best Doctors in the Bay Area" by San Francisco Magazine and Best Doctors, the results of surveys by fellow physicians. His leisure time passion is collecting “egg” images from the contemporary art world and finding life experiences which rise to the “level of art.”

Liyun Li, M.D.

Liyun Li, M.D.Reproductive Endocrinologist

Dr. Liyun Li graduated Phi Beta Kappa from MIT and received her MD with honors from Harvard Medical School, where she studied stem cell biology and cultivated a keen clinical interest in women’s health. After her OB/GYN residency at the University of California, San Francisco (UCSF), Dr. Li completed her Reproductive Endocrinology and Infertility (REI) fellowship at Columbia University in New York, where she trained under the guidance of pioneers in the fields of in vitro fertilization (IVF) and egg donation. During fellowship, her research focused on how obesity and polycystic ovary syndrome (PCOS) affect egg and embryo health. Dr. Li returned to the Bay Area after her fellowship to join the other doctors at PFC, and has since then developed a busy and thriving practice. She believes successful fertility care comes from the formation of a trusting partnership between the patient and the provider. Therefore, she takes a patient-oriented and individualized approach to patients’ care. In addition to her focus in endocrine disorders such as polycystic ovary syndrome (PCOS) and hypothalamic/pituitary dysfunction, Dr. Li sees women and men with a broad range of fertility needs. This includes egg freezing, IVF, comprehensive chromosome screening (CCS), and third-party reproduction using egg donation and gestational surrogacy. She is a skilled surgeon in laparoscopic and hysteroscopic surgeries. Dr. Li is fluent in spoken and written Mandarin Chinese. Her language skills and her unique childhood spent in China, Canada, Europe, and the U.S. has provided her with the inspiration and the drive to take care of the diverse population in the Bay Area and from abroad. In 2014, Dr. Li spearheaded the development of the PFC’s China Patient Program, which has grown consistently each year and earned a reputation in Asia as the place to go for premier fertility services in the U.S. Dr. Li is board certified in Obstetrics and Gynecology as well as in REI, a Fellow of the American Congress of Obstetricians and Gynecologists (FACOG), and a member of the American Society for Reproductive Medicine (ASRM) and the Society for Reproductive Endocrinology and Infertility (SREI). In 2012, Dr. Li was awarded the Best Practicing Physician Research Award for her research presentation on Vitamin D at the Pacific Coast Reproductive Society (PCRS) Annual Meeting. Dr. Li is also the program co-director for the 2018 PCRS meeting. On the weekends, Dr. Li treasures spending a sunny day outdoors with her family and secretly enjoys being an amateur chauffeur for her children to their various play dates and after-school activities.

李立韵医学博士简介 李立韵医学博士出身在中国上海,会说流利的普通话。专业深造在美国,从麻省理工学院生物系本科毕业后,在哈佛医学院获得医学博士 。旧金山加州大学医学院妇产科住院医疗实践, 随后在于纽约哥伦比亚大学医学中心生殖内分泌与不孕不育症专业深造。 因之,李医士得到了很强很严格的医学实践和科学技术的双重基础训练。在哈佛医学院, 她在医学学习的同时从事对干细胞生物的研究, 从而在发育神经科学方面的毕业论文得到了荣誉论文奖。在妇产科住院实践期间,她对各种妇女疾病的治疗都得到了系统地和严格地训练。然而在长期与妇女接触的医疗活动中,她深深地体会到了不孕对于一个育龄妇女和美满家庭的伤害。从而下决心把生殖内分泌与不育症作为她的终生医疗活动和研究方向。她有幸在久负盛名的纽约哥伦比亚大学医学中心实现了自己的理想。她师从著名的生殖内分泌和卵子捐赠的先驱,在全美国培养了许多受人尊敬的生殖内分泌学家。 在导师的指导下,李博士的研究方向是有关卵泡激素如何影响卵子和胚胎质量, 并在这个领域里著名的杂志上发表了多篇文章。在临床方面,她对妇女不孕不育症, 多囊卵巢综合征,内分泌失调和保留生育能力的治疗有独特的心得体会。 李医士已经得到美国妇产科医学专科委员会和生殖内分泌与不育症专科委员会的资格考试和认证。她是妇产科美国国会(American Congress of Obstetricians and Gynecologists), 美国生殖医学学会(American Society for Reproductive Medicine (ASRM) 和生殖内分泌与不育症学会(Society for Reproductive Endocrinology and Infertility (SREI)的会员。

Isabelle P. Ryan, M.D.

Isabelle P. Ryan, M.D.Reproductive Endocrinologist

Dr. Isabelle Ryan is an experienced infertility specialist who offers patients a combination of excellent clinical expertise, strong research experience and warm personal care. She is Board-Certified by the American Board of Obstetrics and Gynecology as a Reproductive Endocrinology and Infertility Specialist. Dr. Ryan takes pride in offering comprehensive fertility care employing all types of fertility treatments including the advanced reproductive technologies (IVF, ICSI, PGD). Dr. Ryan is a fertility specialist who has developed a special interest in treating those with the diagnosis of unexplained infertility and endometriosis. Dr. Ryan is native of New York City and attended the University of California, Davis Medical School. After completion of medical school she was accepted to the prestigious joint Ob/Gyn residency/Reproductive Endocrinology and Infertility fellowship program at the University of California, San Francisco. During her fellowship, she received multiple national recognition awards for excellence in research including the Berlex Scholar's Award. This recognition of her exceptional abilities led to a faculty appointment with the University of California, San Francisco Fertility Group in 1996. During her tenure at UCSF, Dr. Ryan was an integral member of the research and clinical faculty. There, she pioneered research leading to new insights into the important clinical problem of endometriosis-related infertility. Simultaneously she used a very personalized treatment approach to patient care building a successful clinical practice while mentoring and training other fertility specialists. This academic pursuit has led to a unique understanding of endometriosis as well as other infertility diagnoses and a specialized ability to care for these patients. She has published extensively on this subject in professional journals. Her prestigious academic and scientific background and her empathetic approach is a winning combination, much appreciated by her patients.

Dr. Ryan joined the physician staff of fertility specialists at Pacific Fertility Center in 1999. She directs the Third Party Parenting program, and is the Medical Director of Pacific Fertility Center’s Donor Egg Bank, the first independent frozen egg bank in Northern California. Dr. Ryan remains actively involved in research, and supervised the first clinical study at PFC. Dr. Ryan enjoys caring for our international patients. She has had a variety of international experiences, including spending her childhood in France, and studying in China as an undergraduate student. Dr. Ryan has been singled out by her peers as a "Top Doctor" in the national survey Consumers' Research Council of America’s Guide to America’s Top Obstetricians and Gynecologists. In her free time she enjoys sipping wine with friends; watching sunsets on the beach; traveling to remote locations; stretching her intellectual explorations; and encouraging her children to be inquisitive, responsible and embracing of all possibilities.

Eldon D. Schriock, M.D.

Eldon D. Schriock, M.D.Reproductive Endocrinologist

An internationally recognized expert in infertility, Dr. Eldon Schriock has been at the forefront of assisted reproductive technology since 1981. He was a member of the medical team that performed the first in-vitro fertilization treatment in Northern California. Dr. Schriock is Board Certified by The American Board of Obstetrics and Gynecology in both Obstetrics and Gynecology and in Reproductive Endocrinology and Infertility. Dr. Schriock is a native of Ness City, Kansas. He obtained his MD degree in 1977 from Northwestern University where he also completed his residency in Obstetrics and Gynecology. In 1983, he completed a Reproductive Endocrinology fellowship at the University of California, San Francisco. After his fellowship training, he was appointed to the faculty at the University of Tennessee. During his time at the University of Tennessee, he continued his dedication to infertility research and became an expert laparoscopic surgeon. In 1990, Dr. Schriock re-joined the UCSF IVF Program and later became its Director. While at UCSF, he concentrated on infertility patient care and personally treated thousands of patients. Dr. Schriock is a dedicated physician educator, with many of his students currently leading IVF programs across the US, several of whom are practicing in the Bay Area. His innate teaching ability has not only been appreciated by medical students and physicians, but also by his patients and those who attend PFC’s monthly fertility seminars. In November of 1999, Dr. Schriock joined forces with Drs. Herbert, Chenette and Givens, purchased Pacific Fertility Center and became a member of the merged practices known as Pacific Fertility Center.

Dr. Schriock has repeatedly been singled out by his peers in the national survey "Best Doctors in America.” He remains active in fertility research and has authored numerous articles for medical journals. He takes interest in and has expertise with couples whose IVF treatment has been unsuccessful at other infertility clinics. He is keenly attuned to the psychological repercussions of those undergoing ART treatments and works to sensitize the medical community to a psychologically-informed approach to patient care. His interests outside of medicine include spending time with his family and biking, yoga, skiing and meditation.

Joseph Conaghan, Ph.D.

Joseph Conaghan, Ph.D.Laboratory Director

Dr. Conaghan has over two decades of experience in human embryology and is best known for his studies on embryo culture and metabolism. He trained in Embryology and Andrology at the Hammersmith Hospital in London and graduated with a PhD in human embryology from the Royal Postgraduate Medical School at the University of London in 1994. He’s a Board-Certified High-complexity Clinical Laboratory Director in the disciplines of Embryology and Andrology. In 1995, Dr. Conaghan was recruited by the UCSF IVF Program as their Clinical Laboratory Director. He later moved to Pacific Fertility Center in San Francisco where he has been the director since 1999. He is a strong advocate for elective single embryo transfer (eSET) in IVF, and therefore for high standards for culturing and vitrifying embryos. Dr. Conaghan ensures the highest quality of patient care with state-of-the-art-facilities and an experienced team of embryologists and is committed to continuing education for IVF lab professionals.

Recent publications: Conaghan J, Chen AA, Willman SP, Ivani K, Chenette PE, Boostanfar R, Baker VL, Adamson GD, Abusief ME, Gvakharia M, Loewke KE, Shen S., Improving embryo selection using a computer-automated time-lapse image analysis test plus day 3 morphology: results from a prospective multicenter trial., Fertil Steril. (2013) 100(2):412-419 Iager AE, Kocabas AM, Otu HH, Ruppel P, Langerveld A, Schnarr P, Suarez M, Jarrett JC, Conaghan J, Rosa GJ, Fernández E, Rawlins RG, Cibelli JB, Crosby JA., Identification of a novel gene set in human cumulus cells predictive of an oocyte's pregnancy potential., Fertil Steril. 2013 Mar 1;99(3):745-752 Racowsky C, Vernon M, Mayer J, Ball GD, Behr B, Pomeroy KO, Wininger D, Gibbons W, Conaghan J, Stern JE. Standardization of grading embryo morphology. Fertil Steril (2010) 94:1152-3. Pomeroy KO, Harris S, Conaghan J, Papadakis M, Centola G, Basuray R, Battaglia D. Storage of cryopreserved reproductive tissues: evidence that cross-contamination of infectious agents is a negligible risk. Fertil Steril (2010) 94:1181-8. The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting, Alpha Scientists in Reproductive Medicine and ESHRE Special Interest Group of Embryology; Basak Balaban; Daniel Brison; Gloria Calderon; James Catt

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